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Asked by johnm911ky (Male; 28; 28 year old male, 5"9, 235lbs. History of high bp. Treated with lisinopril. Elevated cholestrol. Treated with Simvistatin. Insominia treated with Ambien. Anxiety treated with Clonazepam. Frequent headaches. I suffer from whole body pruritus, with no visible redness or hives (relieved with antihistimines); Relevant drugs:Lisinopril, Ambien, Simvistatin, Allegra, Clonazepam. ) on Sat 19, Dec 2009 08:48pm :
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I RECENTLY SEEN MY FAMILY DR BECAUSE I HAVE BEEN SUFFERING FROM MUSCLE TWITCHES
ALL OVER MY BODY. I HAVE MINOR LEFT ARM WEAKNESS THAT COMES
& GOES. I HAVE ALSO HAD ITCHING ALL OVER MY BODY, WITH NO VISIBLE HIVES OR
REDNESS. MY DOCTOR ORDERED BLOOD WORK WHICH INCLUDED A CBC, LIVER FUNCTION TEST,
PANCREAS TEST, & THYROID TEST. ALL OF MY BLOOD WORK WAS NORMAL, EXCEPT HIGH
CHOLESTROL,& SED RATE WAS 1 POINT TO HIGH. HE ALSO ORDERED A CT SCAN OF BRAIN,
W/ & WO CONTRAST, & A MRI WO CONTRAST OF MY C-SPINE. IM A 28YO MALE, AND
SLIGHTLY OVERWEIGHT.
CT SCAN W/CONTRAST FINDING: AREA OF NODULAR CONTRAST DENSITY IN THE
INTERHEMISPHERIC REGION IMMERDIATELY ANTERIOR TO THE CORPUS CALLOSUM ADJACENT TO
THE ANTERIOR CEREBRAL ARTERIES NOTED, COULD BE A SMALL ANEURYSM. NO OTHER
ABNORMATLITY SEEN. NO PATHOLOGIC ENHANCEMENT. NO EXTRA-AXIAL FLUID COLLECTIONS.
NO EVIDENCE FOR ISCHEMIA OR HEMORRHAGE.
CT SCAN WO CONTRAST FINDINGS: THE GRAY AND WHITE MATTER ATTENUATION ARE NORMAL.
THRE VENTRICLE SIZES, CONTOURS AND CALIBERS ARE NORMAL. NO REGIONS OF ABNORMAL
INTRA-AXIAL OR EXTRA-AXIAL ENHANCEMENT. THE OPACIFIED INTRACRANIAL VESSELS ARE
NORMAL IN CALIBER WITH NORMAL BRANCHING PATTERN. NO VASCULAR MALFORMATION OR
ANEURYSMS SEEN W/ THIS EXAMINE. NO EDEMA (CYTOTOXIC OR VASOGENIC)HYDROCEPHALUS,
INTERCRANIAL HEMORRHAGE, EXTRA-AXIAL FLUID COLLECTIONS, MASS EFFECT OR MIDLINE
SHIFT. NO HERNIATION. NO SPACE OCCUPYING LESIONS EVIDENT. THE CALVARIUM APPEARS
UNREMARKABLE. THE INCLUDED INTRORBITAL STRUCTURES ARE SYMMETRIC IN ATTENUATION,
POSITION, SIZE AND CONTOUR. NO INTRAORBITAL ABNORMALITY SEEN. THE INCLUDED
PARANASAL SINUSES AND MASTOIDS SO NO EVIDENCE FOR ACUTE OR SIGINICANT CHRONIC
DISEASE.
MRI C SPINE FINDINGS: NORMAL CERVICAL VERTEBRAL HEIGHTS, MARROW SIGNAL,
ALIGNMENT. NORMAL ALIGMENT OF THE FACETS. NORMAL SIGNAL OF THE CERVICAL AND
UPPER THORACIC CORD. NORMAL POSTION OF THE MEDULLOCERVICAL JUNCTION. NO
SIGNIFICANT SPINAL CANAL, LATERAL RECESS OR FORAMINAL STENOSIS. NORMAL MARROW
SIGNALS OF THE OSSEOUS STRUCTURES. NO MARROW EDEMA. NO FRACTURE. NO VERTEBRAL
SUBLUXATION. NO ADVANCED DEGENERATIVE CHANGES OF THE FACETS. C5-C6 LEFT
PARASAGITTAL BROAD-BASED DISC PROTRUSION MINIMALLY INDENTS THE LEFT ANTERIOR
MARGIN OF THE CORD AND MAY RESULT IN MASS EFFECT ON THE LEFT C-6 VENTRAL NERVE
ROOT BRANCH, THE MILD C6-C7 DISC PROTRUSION APPEARS INSIGNIFICANT. THE MILD
C3-C4 VERTEBRAL SPURS ALSO APPEAR INSIGNIFICANT. NO CORD SIGNAL ABNORMALITY, NO
SYRINX OR CORD EDEMA. NO CIRCUMFERENTIAL CORD COMPRESSION. UNREMARKABLE
APPEARANCE OF THE INCLUDED UPPER THORACIC REGION. NO ACUTE CERVICAL ABNORMAILTY
SEEN.
IM HAVE BEEN WORRIED ABOUT DISEASES SUCH AS MS AND ALS, AND THE POSSIBLE
ANEURYSM HAS ME CONCERNED. DO YOU THINK IF I HAD MS OR ALS, SOMETHING WOULD HAVE
APPEARED IN THESE PROCEDURES? I HAVE WORRIED MYSELF SICK OVER IT, AND MY DR
DIDNT REALLY TELL ME MUCH, HE JUST REFERED ME TO HAVE A MRA.
SORRY THIS IS SO LONG, I JUST WANTED YOU TO HAVE THE BEST SNAPSHOT OF MY CURRENT
HEALTH STATUS. THANKS SO MUCH, JOHN
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Answer by Dr. A. Srivastava (doctor) on Sat 19, Dec 2009 09:53pm:
Dear John, Thank you for your question. Although without being able to examine you or clinically correlate
your reports I can not offer you the specific advice on diagnosis and treatment that you need, but I would try
to provide you some relevant information about your health concern. Aneurysm mostly remains asymptomatic until
ruptured therefore this positive finding is almost insignificant but needs to be clinically correlated.
Generally pain/numbness in the arm, shoulder and muscle twitches originates from the neck problems due to
irritation in the cervical (neck) spine since the nerves that supply these areas start in the upper cervical
spine (as your reports has shown minor disc protrusion at cervical disc though insignificant). Mostly, this
kind of pain aggravates after turning head and typically occurs in patients with previous neck injuries that
causes disc bulge and in patients with marked arthritis of the upper cervical spine. This pain exacerbates
with prolonged sitting in a stooped posture and when working on a computers for long hours. Additionally,
amyotrophic lateral sclerosis (ALS) may show earliest symptoms of muscle twitching, cramping, weakness
affecting an arm/leg, slurred speech; difficulty chewing and swallowing. And, in multiple sclerosis symptoms
could be loss of muscle coordination & strength, normal sensation and vision so it is worth consulting an
evaluation to rule out these conditions as well. For general pruritis, you need to consult your treating
doctors as the medicines you are taking their side effects can be most likely cause of this. I would also
recommend evaluating the possibility of general anxiety disorder and ruling out this with your treating doctor
for your clonazepam dose. If you suffer continuous pain, numbness, twitching at these areas, please arrange an
appointment with a neurologist right away who will evaluate the possibilities here and can provide you an
appropriate treatment. Further referral to a physiotherapist for spinal exercises could be beneficial and may
produce relief of symptoms. Hope this information proves helpful to you. Take Care & Regards!!!
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This questions is open for comments. Please share your opinion.
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Comments:
Response by Dr JS Anand on Sun 20, Dec 2009 12:33pm:
Hello,
Welcome to the AMD forum of doctors. Dr Anurag has very nicely explained the possibilities for your symptoms.
From your CT head the possibility of minor aneurysm is there. In a cerebral aneurysm, there is a weakness in
the wall of a cerebral artery or vein causes a localized dilation or ballooning of the blood vessel. Since it
is a small one, so there is no need to panic now but I completely agree with your doctor that you have to get
MRA(magnetic resonance angiography) done which is the gold standard(although invasive) of detecting any
vasospasm. It is true that multiple sclerosis usually presents with involuntary muscle spasms and altered
changes in sensations, but any changes are detected on MRI head and spine. Your MRI spine and CT head are
absolutely clear on this. But to clear your doubts, you can get CSF analysis and evoked potentials done.
Regarding ALS, MRI scans are usually normal even in patients of ALS. Best would be to get an electromyography
and nerve conduction velocity test done in addition. Your MRI spine is showing mild disc protrusion at c6-c7
levels. This may be responsible for arm symptoms that you are having. Regarding muscle twitching, it can be
found in other medical causes like acid-base imbalance in the body, low sodium,calcium and vit D deficiency,
muscle fasciculation syndrome(a disorder of the nervous system characterized by the uncontrolled twitching
(fasciculation) of muscle groups in various parts of the body), chronic fatigue syndrome, hypoparathyroidism
and spinal muscular atrophy. So my sincere advice would be to consult a neurologist and get evaluated for
these possibilities. Since you do not have any rash on the body but itching is there, so I would suggest you
to get neuropathic itch ruled out. I hope it helps. Take care and please do keep us posted in case you have
any additional queries. Kind regards.
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