I noticed on Sunday that I was starting to get a sore throat but I didn't think much of it since I've gotten several colds this fall and they all started with a sore throat. Over the past few days, my sore throat has not gotten better and I think might a

	Asked by writerchick303 (Female; 19; I'm allergic to penicillin. Growing up, I frequently got sore throats and had strep numerous times.; Relevant drugs:I got the vaccination for H1N1 on Monday. ) on Thu 10, Dec 2009 11:20am :
	I noticed on Sunday that I was starting to get a sore throat but I didn't think much of it since I've gotten several colds this fall and they all started with a sore throat. Over the past few days, my sore throat has not gotten better and I think might actually have gotten worse. Only the left side of my throat is swollen, it is uncomfortable to swallow and just using the muscles around my neck make my throat hurt. There are also several large and defined spots that look almost like blisters. The left side of my neck is also stiff. There are at least three large knots in my neck muscles that I first noticed on Monday. They are large enough to be noticeable. They have not gotten better since then and I have tried relaxing my neck and using a heat pad. I have also been taking acetaminophen.
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	Answer by Dr.Kokil Mathur (doctor) on Thu 10, Dec 2009 06:02pm: Hi Welcome to the AMD forum! If you started to get a sore throat on Sunday and took the H1N1 vaccine on Monday, then there are two possibilities that you should look into. One is that it is a case of H1N1 that could not be prevented with the shot as the symptoms had already started or any other case of viral flu. It could also be a streptococcal sore throat with enlarged neck glands. Since you have neck glands (knots, swollen lymph nodes) and a sore throat it can also be an EBV or infectious mononucleosis (mono) infection. What I mean by that it is a case of infection not related to vaccine. Since the infection stated prior to vaccination, the vaccination could not prevent the infection. In such a case you would need to consult your PCP or ENT and need to take complete course of antibiotic, anti inflammatory along with warm saline gargles and drinking warm fluids like soups, ginger tea, warm lemonade etc. Your doctor may order a throat swab, blood tests and a N1N1 test to be sure of diagnosis. The other possibility is that a sore throat that had already started acted as a base for the H1N1 vaccine to cause an infection. This would indeed be a very rare case. You can talk to the doctor and if they feel that vaccine complicated the sore throat then you can inform the concerned authorities. This would also depend on which vaccine you got—adjuvinated or the unadjuvinated. The unadjuvinated does not have the immune booster and is recommended only for high risk polpulation. The adjuvinated one has immune boosters and is given to the general population. For more information you can read: http://www.cdc.gov/h1n1flu/vaccination/vaccine_safety_qa.htm It is difficult to comment beyond this at this stage. Discuss this with your doctor and get yourself examined. Please let me know if there is any thing else and do keep me posted. Take care!
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	Comments: Response by Dr. A. Srivastava on Thu 10, Dec 2009 09:05pm: Hello Madam, I completely agree with Dr Kokil that if the symptoms have started well before the vaccination then vaccine may not help in this regard. Sore throat is commonly associated with either some kind of viral infection or streptococcal infections. I too will agree with Dr Kokil that a throat swab test and blood tests with the help of a doctor may help you reach to a diagnosis. Though a possibility of H1N1 can not be denied unless tested but I would advice you to keep a check on dehydration, vomiting, associated diarrhea and respiratory distress which is commonly seen in H1N1 and not in Common flu and streptococcal infection. Rest whole information is nicely told by Dr Kokil. Hope this information helps and do keep us posted in case of further help.
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