Regulating irregular periods

	Asked by Unregistered (Female; 51; I had an ultrasound and was told i had fibroids and an abnormally thick uterus walls. After that I had a biopsy of the uterus wall, no cancer was found, but was told this condition could lead to cancer. See my question for more details. ) on Wed 29, Oct 2008 11:03pm :
	I'm a 51 yr old female I have been perscribed Northindrone Acetate to regulate irregular periods. I have been reading about this drug and am very concerned about the side effects. I have high blood pressure and take metoprolol, also am working on lowering high cholestrol with diet. Both of these condidtions are listed on the drugs info sheets as something to be concerned about. Could you please shed some more light on this topic for me. Side effects include heart attack and stroke, both which I feel I am already at high risk for. So I am kind of scared to take this medication. Are there safer alternatives. Thanks
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	Answer by Dr Paul S, MD (doctor) on Thu 30, Oct 2008 12:05am: Hi. I believe that in your situation, there should be a balance between the risks and benefits of such treatments. While chronic thickened endometrium may increase your risk of developing endometrial cancer, I think the this risk is somewhat less than the risk of developing heart and vascular problems from taking the hormonal drug. This drug may also affect the way your body handles lipids and cholesterol. I could think of two solutions for this. One is that you can continue this hormonal drug, but at the same time take other drugs that will lower your risk of cardiac events such as that of cholesterol lowering drugs. Another solution is you can discontinue this hormonal drug, but make sure you have serial transvaginal ultrasounds to monitor the thickness of the endometrium. I suggest that you discuss this at depth with your gynecologist and cardiologist and I'm sure you can strike the proper balance between all the risks and benefits. Regards.
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