This question was answered on Fri 19, Mar 2010 02:53am by Dr. Harsha Priolcar

Reasons for Decreasing eGFR?

    
Asked by angelkissed (Female; 38; UNITED STATES; 30 lb. unexplained weight loss, low normal weight (117 lbs.), low B12 (corrected with supplements), hypovitaminosis D (corrected with supplements), sudden increase in triglycerides (total, HDL and LDL all good), migraine, subclinical hypothyroidism in remission (no medication), left lateral neck mass (being investigated), normal BP, 20-year smoker (quit in 2007), moderate alcohol use (4 drinks/week), no drugs, severe MRI contrast allergic reaction (anaphylaxis/shock), no children or hormones ever; Relevant drugs:Topiramate 50 mg. (migraines), vitamins ) on Thu 18, Mar 2010 11:09am

Since July, my eGFR has steadily decreased. 59 (July), 59 (December), 57 (February), and now 54 (March). Labs reveal no proteinuria, hematuria, etc. No fever. No other signs of infection. No consistent urinary symptoms. Positive CVA tenderness sign in January, and achy (not colicky) pain for months above left flank area, though now decreased. Renal ultrasound was unremarkable aside from "moderately small" kidneys bilaterally (nephrologist said this was insignificant since I am small-framed). Urine albumin/creatinine was normal. My BMI is about 19. I haven't been exercising much at all due to not feeling well, do not consume excess protein, and have labs drawn fasting (as instructed). Nephrologist said, "It's not your kidneys." Then what is it? What could cause decreasing eGFR with this medical history and current clinical profile? Other labs are OK, but my PCP is somewhat indirect, and orders a comprehensive metabolic panel alone for almost everything. Sometimes lipids, urinalysis or CBC, but nothing specialized.

Actions: | Forward |
Answer


Name 

Email 

Security code
Enter the text as shown above


E-Mail me when someone replies to this post
Answer by Dr. Harsha Priolcar  on Fri 19, Mar 2010 02:53am:


If you find the site useful, please consider making a donation.  Click the button to donate.   

Please rate my answer (select the stars, no need to log in.)  

Comments:

Comment by Dr.Ravindra Rajput on Fri 19, Mar 2010 07:39am:
Hi, Dr. Harsha Priolcar has ruled out all the causes for low eGFR and as well as explained quite well. Another important factor for low eGFR is volume depletion. If there is volume depleted state due to chronic dehydration, and if body compensatory mechanism is unable to retain the blood volume to normal level, can also lead to low eGFR. In such cases you need to take adequate fluids. Sometimes ultrasound may not detect other causes properly renal vein thrombosis, renal infarction and renal artery stenosis. In such cases color doppler and MRI will detect it with high precision. Any connective tissue disorder (SLE) if present should be ruled out. You also need to undergo blood tests like complete blood count, peripheral smear and ESR. And as Dr. Harsha Priolcar said, update your progress and we are there to help you. Take acre and regards.

This question is open for comments.  Please share your opinion.

Comments


Name 

Email 

Security code
Enter the text as shown above


E-Mail me when someone replies to this post


 
What users are searching right now on Ask Medical Doctor:
Iexperiencenumbnessfro92656 Enter your comments here diabetes     Iexperiencenumbnessfro92656 Enter your comments here relevance     Iexperiencenumbnessfro92656 Enter your comments here remove     leg pain with ckd     indirect coobs     motrin     lateabortions     nitrofuaration     ars weeks     IsitsafetouseGTNsprayonthepenisforerectiledysfunction     sex photos     HASAprogram     pankaj     symptoms of underactive thyroid     Possible Rabies infection from bat without direct contact with the animal     bleedingaftermenopause     adenocarcinome of the breast     maxaltandadvil     Can20we20sadden20God     numbwhitefingers     growthofpenisis     dizzyspellslightheaded     ihavehard     femoral hernia     function valueOf native code     Aftergettinghitundertheribcagedu     what is a home remedy for a cold sore     Tamifluhighbloodpressure     meds for burping     Ihavepaininmylowerbackandlowerstomach     how20long20does20semen20live20outside20a20person20body     if the 3 years are done for the implanon will it completely stop working or i will have to get it removed     feel pressuretighten Neck is stiff but confined to neck and shoulde     Late period     Searchforanswersscriptalert42873script     oral herpes     bursitissurgerg     Search for answers     heel and leg pain     Search for answers     protein     Yeast20Infection     penisinsideout     boob     melanomacoughing     canyougivesingulairandclaritinatthesametime74787     how much vitamin d should be in the body     Search for answers     bladder infections     potts     leg anatomy     detoxmarijuana     ironinjectable     upchar bavasir     neuropathy     Sudden bruising     losingmymemory     Headache     HBVDNANEGATIVEMEANSFREEFROMHEPATITIESBVIRUS     PICTURES OF QUATER SIZED RASH     Is it Free     cansuturematerialleftnearlowerpelvismakeitswaytothebrain     Tamifluhighbloodpressure     what is a home remedy for a cold sore     Aftergettinghitundertheribcagedu     function valueOf native code     femoral hernia     ihavehard     dizzyspellslightheaded     growthofpenisis     numbwhitefingers     Search for answers     Can20we20sadden20God     Search for answers     maxaltandadvil     adenocarcinome of the breast     bleedingaftermenopause     Possible Rabies infection from bat without direct contact with the animal     symptoms of underactive thyroid     pankaj     HASAprogram     congested spleen     does not appear to be a fibroadenoma     what is stage 4 prostage cancer     osteo arthritus     whatismaximumsmallestpenis     discolored     what should my potasium levels me     back pain     peptic ulcers     Search for answers     what causes sweating a pinkish tint     VAGINAL ODER     at what point do you have discomfort with hepatitis c     prag     phneumonia     rash only on leg     Genitalitching92654 Enter your comments here he     Hast methan kaise addat hate     NeverEjaculatedDischarg92658 Enter your comments here nauseous     Iexperiencenumbnessfro92656 Enter your comments here away     MissedMenstrualCyclebladder     bump on ovarie     sinosam 200     feeling like the floor is shaking     belly button pus     celexa     lackenergy     Heart skip     luteal     swag disease     Tho     sun burn     i have a likoria of probem plz guide me and simple treatment     growthofpenisis     dizzyspellslightheaded     ihavehard     femoral hernia     function valueOf native code     MissedMenstrualCyclebladder     Aftergettinghitundertheribcagedu     what is a home remedy for a cold sore     Tamifluhighbloodpressure     cansuturematerialleftnearlowerpelvismakeitswaytothebrain     Is it Free     PICTURES OF QUATER SIZED RASH     HBVDNANEGATIVEMEANSFREEFROMHEPATITIESBVIRUS     Headache     losingmymemory     Sudden bruising     upchar bavasir     detoxmarijuana     IhavearashinmybuttocksareaIhavebeen     strange feeling in left of chest     mastribution     what causes sweating a pinkish tint     Search for answers     peptic ulcers     Search for answers     

©2011 - Ask Medical Doctor  |  All Rights Reserved
The site is not a replacement for professional medical opinion, examination, diagnosis or treatment. Always seek the advice of your medical doctor or other qualified health professional before starting any new treatment or making any changes to existing treatment. Do not delay seeking or disregard medical advice based on information written by any author on this site. No health questions and information on AskMedicalDoctor is regulated or evaluated by the Food and Drug Administration and therefore the information should not be used to diagnose, treat, cure or prevent any disease without the supervision of a medical doctor. Posts made to these forums express the views and opinions of the author, and not the administrators, moderators, or editorial staff and hence AskMedicalDoctor and its principals will accept no liabilities or responsibilities for the statements made.

Home | Terms & Conditions | Contact Us | Frequently Asked Questions | Disclaimer | Privacy Policy | Advertise with us
Stats