This question was answered on Fri 19, Mar 2010 02:53am by Dr. Harsha Priolcar

Reasons for Decreasing eGFR?

    
Asked by angelkissed (Female; 38; UNITED STATES; 30 lb. unexplained weight loss, low normal weight (117 lbs.), low B12 (corrected with supplements), hypovitaminosis D (corrected with supplements), sudden increase in triglycerides (total, HDL and LDL all good), migraine, subclinical hypothyroidism in remission (no medication), left lateral neck mass (being investigated), normal BP, 20-year smoker (quit in 2007), moderate alcohol use (4 drinks/week), no drugs, severe MRI contrast allergic reaction (anaphylaxis/shock), no children or hormones ever; Relevant drugs:Topiramate 50 mg. (migraines), vitamins ) on Thu 18, Mar 2010 11:09am

Since July, my eGFR has steadily decreased. 59 (July), 59 (December), 57 (February), and now 54 (March). Labs reveal no proteinuria, hematuria, etc. No fever. No other signs of infection. No consistent urinary symptoms. Positive CVA tenderness sign in January, and achy (not colicky) pain for months above left flank area, though now decreased. Renal ultrasound was unremarkable aside from "moderately small" kidneys bilaterally (nephrologist said this was insignificant since I am small-framed). Urine albumin/creatinine was normal. My BMI is about 19. I haven't been exercising much at all due to not feeling well, do not consume excess protein, and have labs drawn fasting (as instructed). Nephrologist said, "It's not your kidneys." Then what is it? What could cause decreasing eGFR with this medical history and current clinical profile? Other labs are OK, but my PCP is somewhat indirect, and orders a comprehensive metabolic panel alone for almost everything. Sometimes lipids, urinalysis or CBC, but nothing specialized.

Actions: | Forward |
Answer


Name 

Email 

Security code
Enter the text as shown above


E-Mail me when someone replies to this post
Answer by Dr. Harsha Priolcar  on Fri 19, Mar 2010 02:53am:


If you find the site useful, please consider making a donation.  Click the button to donate.   

Please rate my answer (select the stars, no need to log in.)  

Comments:

Comment by Dr.Ravindra Rajput on Fri 19, Mar 2010 07:39am:
Hi, Dr. Harsha Priolcar has ruled out all the causes for low eGFR and as well as explained quite well. Another important factor for low eGFR is volume depletion. If there is volume depleted state due to chronic dehydration, and if body compensatory mechanism is unable to retain the blood volume to normal level, can also lead to low eGFR. In such cases you need to take adequate fluids. Sometimes ultrasound may not detect other causes properly renal vein thrombosis, renal infarction and renal artery stenosis. In such cases color doppler and MRI will detect it with high precision. Any connective tissue disorder (SLE) if present should be ruled out. You also need to undergo blood tests like complete blood count, peripheral smear and ESR. And as Dr. Harsha Priolcar said, update your progress and we are there to help you. Take acre and regards.

This question is open for comments.  Please share your opinion.

Comments


Name 

Email 

Security code
Enter the text as shown above


E-Mail me when someone replies to this post


 
What users are searching right now on Ask Medical Doctor:
buntis ba ako     round bruises that is expanding     drsears     whatdopusscomingouttheendofyourpenismean     period stopped after a day and a half and I had brown and pink spotting     symtemchecker     broken hand     spinalstingingpain     Ask a medical doctor a question for free     besttreatmentforregularmenstrulcycle     9montholdbabywithvitiligo16845cura     sliced tow     lumpinelbowcrease     Hi last night i had sex for the first time n top my penis was hurting n i couldnt come n in d morning i masturbated n now my penis skin is swollen n the top of my penis was hurting very badly as soon as it touched my jeans or boxers i am really worri     high monocytes     sciatica     How do I stop Vaginal Thrush from itching     lost voice     Can levsin show up on a drug test     hast methon ko chhodne ke upay     ho ould i knoww if i had aids     dyguesia     2nd degree burn from boiling water throbbing leg     samb     lipotropic injections     dizzy stomach     HGC DIET     ax     my15yearoldsonhasa     Search for answers     been     rectal numbness     FLAT     corn on foot     typesofleucorrhoea     Isitbadtogiveaninfantsomecoldmillkinsteadofwarm     renaldisease     TESTESTERONE     EMOSTIONAL FOR NO REASON     protraced eyes     Yeast infection monistat     Xrockme     Search for answers     itchy scalp     Search for answers     lung transplant     Search for answersi have theses stange deep purple marks on my back they look like scars but i havent got any cuts latley what are they     name of vaginal cream for likoria     canitakeapercocetwithmusinexdm42673     iwasdiagnosedwithcellulitisonmyupperrightthighons     ceilulitas     IfpatientallergictoEpinephrine     fear     one side respiratory     HowmanydaysamanlivewithoutbothWaterandFood     WhatdoesABSINTERP     is there a cure for women losing there hair like thinning or sheddingcom     isitokaytotakesuphedrinewithcelexa     left stomach pain dizzy ear ache and fever     IshavingaCorticalthicknessof17cmwithinnormalsize     lots of sex     Infected toe corn     causeoflargepolyps     projectile     condom stuck vagina     sexwithoutcumminginside21225     Ihavedryskinwith     availabilityofoxacillin     Cirrhosis of the liver a disease commonly associated with alcoholism     docter i had gone to a strip club with many friends two days beforein there a stripper approached me and when i said no she pinched my neck and walked offi have not had sex with anyone till now in my lifebut now when i look the area wer she piched     BRACCYACARDIA     chlamydia throat     swinefluvaccine     which finasteride is better between cipla and curlzfin     hematocrit 287     how to get rid of likoria     oneofmyboobsisconstantlyitchinginthe     what is lukeria     is white flakes on breast safe     pain swallowing     my 11 year old has back pains     does too much calcium cause stomach disorders     buprion and nyquil     ingrown hair vagina     transvginal     does mastribution damage sperm     betterhomesandgardenscom     Ivedevelopedahardlumbbelowmyright     dry nipple     Odor from the viginia     hard lump on rib     Stomache olster     havingwhitelookingwormsthesizeofricecomingoutofyourvagina     going     birlum meal     Chill in my leg     lechorea     bump on forehead     HEART RATE EXERCISE     what is ivf_c why do v take it     itchy palms     Shou     Ifyouaredehydratedandhaventurinatedalldayandthe     Can use ipill for 15 aged girl     Can u give a guy genital herpes from a cold sore     Burningduringurinationlowerstomachbackcrampscloudy     Alcohol and mono     what are scabies     Erec     while     small pimples on back of arms     syptoms of iron deficency     whatkindofantifungalisusedtotreatringworm     polyclav 625 uses     HOW MANY DAYS HAVING SEX AFTER OPRATION     Ginko     Howshoulditreatamissedshotofmeth     hands and legs trimble     MysevenyeRoldhasdischarge     kidney stones     pea siized nodulecyst attached to collarbone     scaloped     whats the best ingrdients for probotics     Is it safe to take Mersyndol and duromine     swelling and itching of hands after drinking     I had a varicocele embolization exactly a week ago When can I resume sexual activity masturbation and sex     Ife     Ihaveadrypatchofskinonmyscalpthatfeelslikeasca     brusing     swollenglands     HelloIamveryworrieda92652 Enter your comments here moderator     can you take mucinex and niquil together     Dr brayan samarasinghe     heart vowel     Search for answers     palecoloredstool     Search for answers     ResultSallwizeawals     head neck     

©2011 - Ask Medical Doctor  |  All Rights Reserved
The site is not a replacement for professional medical opinion, examination, diagnosis or treatment. Always seek the advice of your medical doctor or other qualified health professional before starting any new treatment or making any changes to existing treatment. Do not delay seeking or disregard medical advice based on information written by any author on this site. No health questions and information on AskMedicalDoctor is regulated or evaluated by the Food and Drug Administration and therefore the information should not be used to diagnose, treat, cure or prevent any disease without the supervision of a medical doctor. Posts made to these forums express the views and opinions of the author, and not the administrators, moderators, or editorial staff and hence AskMedicalDoctor and its principals will accept no liabilities or responsibilities for the statements made.

Home | Terms & Conditions | Contact Us | Frequently Asked Questions | Disclaimer | Privacy Policy | Advertise with us
Stats