This question was answered on Mon 07, Apr 2014 06:51am by Dr.Kokil Mathur

Hello - my daughter, age 28, has been on subutex for 1+ years, she has been offfor 15 days and it is still showing up in her urine. Is this possible? If so,how much longer would you expect it to show up?

    
Asked by Unregistered (Female; 28 ) on Mon 07, Apr 2014 04:56am
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Hello - my daughter, age 28, has been on subutex for 1+ years, she has been off for 15 days and it is still showing up in her urine. Is this possible? If so, how much longer would you expect it to show up?

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Answer by Dr.Kokil Mathur  on Mon 07, Apr 2014 06:51am:

Hi! Subutex contains Buprenorphine, and approximately 95% of a single prescribed dose is eliminated from the body in about 144 hours, mainly in the feces (68%) and partly in the urine (27%). Buprenorphine has a plasma half life of 37 hours, so complete elimination is expected by 6-7 half lives. So, for a single dose, most of the drug of should be excreted by 6-7 days. In reality, since it has a half life of about 37 hours, it will take about 10-12 days for most of the drug to get excreted. However, in slow metabolizers, in those still abusing the drug and in those who have been taking it for long, a sensitive test may detect small amounts of buprenorphine for 10-15 days as well. Please let me know if there is any thing else and do keep me posted. Take care!

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Comment by Dr Arti Sharma on Tue 08, Apr 2014 01:18am:
Hello and thank you for posting on the forum.Subutex is buprenorphine . The half life of Suboxone is about 24-72 hours. It takes about five-seven half lives before medication is out of your body. I agree with Dr. Mathur that it may take almost 1012 days for the drug to be completely excreted from our body. Many sensitive tests can detect small amounts of buprenorphine also. Do write to me again with more queries. I sincerely hope it helps.Best luck and kind regards!

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