Diabetic Meds- Concerned about long term complications related to use

	Asked by Unregistered (Male; 38; LDL/HDL Issues. New Onset Type II Diabetic. No hypertension or cardiac related issues. Family history of Diabetes. ; Relevant drugs:Actos, Metformin, Lovaza, Lantus, Glipizide ) on Thu 25, Dec 2008 06:16am :
	I am a new onset Type II Diabetic and have been prescribed the following meds. Actos, Metformin, Glipizide and Lovaza. I was on Lantus but that has been discontinued. Since my diagnosis just over two months ago, I've lost over 35 pounds, controlled my diet and added daily physical exercise. I don't drink alcoholic beverages nor do I have hypertension or other related cardiac history. I do smoke cigarettes on occasion ( one or two a day ). Are there any long term health concerns directly related to my newly prescribed meds? Thank you. Mike O
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	Answer by Dr Rowena S, MD (doctor) on Fri 09, Jan 2009 02:08pm: Hi, Thank you for posting. It is good that you are having a healthy lifestyle: You lost weight, controlled your diet and have a daily exercise regimen. Type 2 diabetes is a lifelong disease marked by high levels of sugar in the blood. It begins when the body does not respond correctly to insulin, a hormone released by the pancreas. The immediate goal of treatment is to lower high blood glucose levels. The long-term goals of treatment are to prevent diabetes-related complications, such as:amputation of limbs, blindness, heart disease or kidney failure. The primary treatment for type 2 diabetes is exercise and diet. Medications are given to help maintain normal or near-normal blood glucose levels. Biguanides or Metformin tell the liver to decrease its production of glucose. This decreases glucose levels in the bloodstream. Glipizide belongs to the oral sulfonylureas trigger the pancreas to make more insulin. While Actos or piolgitazone help insulin work better at the cell site. Studies show that there are no long term effects seen, though some increases the risks for heart problems. However, if you can control your glucose with diet and exercise, you may discuss this with your doctor. Some diabetics can control their blood glucose levels when they reach their ideal weight. Regular follow-up is highly recommended. Take care and regards.
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