This question was answered on Thu 10, Feb 2011 10:53pm by Dr Sanjivani Wanjari

CHANGING ANTIBIOTICS

    
Asked by Unregistered (Female; 73; UNITED STATES; Hep c; Relevant drugs:Amox-clav 865 ) on Thu 10, Feb 2011 10:14pm
Priced at $9.00

Could I safely change to Keflex?

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Answer by Dr Sanjivani Wanjari  on Thu 10, Feb 2011 10:53pm:

Hello, few details regarding the need of antibiotics and the condition for which you are taking those would be appreciated. Keflex is a first-generation cephalosporin antibiotic. Keflex is used to treat infections caused by bacteria, including upper respiratory infections, ear infections, skin and urinary tract infections. Serious interactions of cephalexin with other drugs are uncommon and hence switching over to keflex from amox clav should not be a problem. But you are having hepatitis C. Hepatitis C is a viral infection that causes inflammation, cirrhosis and scarring of the liver tissue. There is also an alteration in liver enzymes and this might affect the metabolism and excretion of the drugs. There is evidence to show that liver function impairment increases both the apparent half-life of elimination and the urinary excretion of the drug. If you have kidney or liver disease, a stomach or intestinal disorder such as colitis, or diabetes etc, you may need a dose adjustment. Liver function tests may also be done before starting Keflex. The drug can also cause certain side effects like diarrhoea (usually mild), dizziness, headache, indigestion, joint pain, stomach pain (usually mild) and tiredness etc. Hence I suggest that you consult your Doctor for the correct antibiotic and appropriate dosage of the drug. Hope this helps. Take care and good luck.

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